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The wrangling over what to do about a sprawling homeless camp in Santa Rosa, Calif., highlights how hard it is to find answers for a growing crisis across California and much of the West.

Some people struggling with opioid addiction who switched to kratom swear the herb salvaged their lives. But federal agencies and the brother of a man who died from his kratom use warn of its risks.

Life expectancy in the U.S. has taken a significant downward turn. This is especially true in Ohio and West Virginia, which have the highest rates of overdose deaths among people ages 25 to 64.

North Korea has threatened to send a "Christmas present" for the United States if sanctions aren't eased by the end of the year. Trump says he isn't worried about it.

Food waste is bad for your wallet and the planet. These tips and tricks will help you preserve food longer, cook more creatively and ultimately save food — a precious resource — from the landfill.

NPR tells the exclusive, behind-the-scenes story of the first person with a genetic disorder to be treated in the United States with the revolutionary gene-editing technique CRISPR.

We profiled women who were on the front lines of social change this year — from a doctor fighting Ebola in Congo amid gunfire to two forthright beauty queens.

To celebrate Christmas, Fresh Air listens back to a concert given by the late singer and actress on Feb. 11, 1997. Clooney spoke about her childhood and working with Bing Crosby and Billy Strayhorn.

The playlist is a carefully curated selection of Latino artists who created intriguing, unforgettable and soul-boosting sounds.

Here are images that resonated from the year: photos of families facing difficult decisions on the U.S. border, illustrations showing the struggles of student loan debt and otherworldly portraits.